What happens if you do not use Misoprostol in time after mifepristone?

Women on Web advises you to use Misoprostol 24 hours after swallowing the Mifepristone tablet. However, it can also be used later, up to 72 hours after swallowing Mifepristone.

The World Health Organization advises on a regimen that starts with Mifepristone 200mg and is followed 1-2 days later by 800 mcg of Misoprostol. The minimum recommended interval between use of mifepristone and misoprostol is 8 hours.

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Research has shown that for women with pregnancies of 8 weeks or less, Misoprostol works with the same efficacy whether it is taken at 12 hours, 24 hours, 48 hours, or as much as 72 hours after Mifepristone. Though we instruct women to take Misoprostol 24 hours after Mifepristone and strongly encourage women to follow all the instructions for proper use, if a woman takes it slightly earlier or later, this does not affect the outcome of the medical abortion.

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